
⸺ Synova Research
Melanocortin receptor agonist (bremelanotide) studied in animal models for central nervous system pathways of arousal.
Secure checkout via UK open banking. Free shipping on orders over £100.
Independently tested
COA on request
Next-day UK dispatch
Order before midnight
Research use only
Not for human consumption
⸺ Important
⸺ Overview
PT-141, also known as bremelanotide, is a cyclic heptapeptide derived from Melanotan II. Unlike the vascular mechanisms studied elsewhere, research interest centres on central melanocortin signalling in the brain.
⸺ Mechanism of Action
It acts primarily on MC3 and MC4 melanocortin receptors in the hypothalamus, influencing dopamine-related pathways in the central nervous system rather than acting on peripheral blood vessels.
⸺ Research
Animal studies examine MC4 receptor activation and downstream neurotransmitter changes.
Preclinical rodent work has investigated arousal-related behavioural endpoints.
In vitro research characterises binding profiles across the melanocortin receptor family.
Summarised from preclinical literature for informational purposes only. Not medical or veterinary advice. Synova Research products are sold strictly for in-vitro and laboratory research.
⸺ Details

Investigational triple receptor agonist targeting GLP-1, GIP and glucagon — studied in animal models for appetite control, energy expenditure and glucose balance.

Dual GLP-1 and GIP receptor agonist studied in preclinical models for glucose regulation, insulin sensitivity and energy balance.

Synthetic analogue of the GLP-1 hormone used in research to study glucose regulation, insulin secretion and the incretin response.