⸺ Synova Research
MOTS-c
Mitochondrial-derived peptide studied for metabolic regulation, insulin sensitivity, exercise response and cellular stress resistance.
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Research use only
Not for human consumption
⸺ Important
- • Peptides sold in lyophilized form
- • Strictly for laboratory research
⸺ Overview
About MOTS-c
MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial genome. Researchers investigate it as a regulator of metabolic homeostasis, with particular interest in how it influences glucose handling, insulin sensitivity and the cellular response to exercise.
⸺ Mechanism of Action
How it works
MOTS-c influences the AMPK signalling pathway — a master regulator of cellular energy. Through AMPK activation, animal studies report improvements in glucose uptake, fatty acid oxidation and resistance to metabolic stress, alongside changes in mitochondrial function.
⸺ Research
Areas of study
Insulin sensitivity
Rodent studies show improved insulin sensitivity and glucose disposal following MOTS-c administration, particularly under high-fat-diet conditions.
Exercise response
Preclinical work suggests MOTS-c modulates skeletal-muscle adaptation to exercise via AMPK signalling.
Cellular stress resistance
Research has examined MOTS-c in models of metabolic and oxidative stress, with reported protective effects on cellular function.
Summarised from preclinical literature for informational purposes only. Not medical or veterinary advice. Synova Research products are sold strictly for in-vitro and laboratory research.
⸺ Details
Specification
- CAS
- 1627580-64-6
- Intended use
- Research use only.
- Storage
- Lyophilised: cool, dry, dark. Reconstituted: refrigerate at 2–8°C.
- Solubility
- Vial holds up to 3mL.
- Shelf life
- Lyophilised: up to 24 months. Reconstituted: 4–6 weeks refrigerated.
- Handling
- Maintain sterile technique.
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