⸺ Synova Research
Melanotan II
Synthetic analogue of α-MSH studied for melanocortin-receptor activity, melanin synthesis and UV-independent pigmentation pathways.
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Independently tested
COA on request
Next-day UK dispatch
Order before 2pm
Research use only
Not for human consumption
⸺ Important
- • Bacteriostatic water not included
- • Syringes not included
- • Peptides sold in lyophilized form
- • Strictly for laboratory research
⸺ Overview
About Melanotan II
Melanotan II is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH). It binds melanocortin receptors on melanocytes, stimulating melanin synthesis. Additional receptor activity has been observed in research settings involving pathways associated with libido and other melanocortin-mediated effects.
⸺ Mechanism of Action
How it works
Melanotan II non-selectively activates melanocortin receptors (notably MC1R and MC4R). MC1R activation drives melanin synthesis in melanocytes, producing darkened pigmentation in animal models even with minimal UV exposure. MC4R activity is studied for its role in central appetite and sexual-behaviour pathways.
⸺ Research
Areas of study
Pigmentation pathways
Animal studies show increased eumelanin production in skin and hair following Melanotan II administration, independent of UV stimulation.
Melanocortin receptor signalling
Research explores downstream signalling at MC1R and MC4R, supporting wider investigation of melanocortin biology.
Behavioural studies
Preclinical models have looked at central effects on appetite suppression and sexual-behaviour markers attributed to MC4R activation.
Summarised from preclinical literature for informational purposes only. Not medical or veterinary advice. Synova Research products are sold strictly for in-vitro and laboratory research.
⸺ Details
Specification
- CAS
- 121062-08-6
- Intended use
- Research use only. Reconstitute with bacteriostatic water (sold separately).
- Storage
- Lyophilised: cool, dry, dark. Reconstituted: refrigerate at 2–8°C.
- Solubility
- Bacteriostatic water. Vial holds up to 3mL.
- Shelf life
- Lyophilised: up to 24 months. Reconstituted: 4–6 weeks refrigerated.
- Handling
- Use sterile technique.
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