⸺ Synova Research
IGF-1 LR3
Long R3 analogue of insulin-like growth factor 1, studied in cell culture and animal models for anabolic and cell-proliferation signalling.
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Independently tested
COA on request
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Research use only
Not for human consumption
⸺ Important
- • Peptides sold in lyophilized form
- • Strictly for laboratory research
⸺ Overview
About IGF-1 LR3
IGF-1 LR3 is an extended, modified analogue of insulin-like growth factor 1 with a substantially longer half-life than native IGF-1. It is widely used in in-vitro culture work and preclinical models of growth and tissue signalling.
⸺ Mechanism of Action
How it works
The Arg3 substitution and 13-amino-acid extension reduce binding to IGF binding proteins, so more of the peptide remains active. It signals through the IGF-1 receptor, driving PI3K/Akt pathways associated with cell growth, protein synthesis and glucose uptake.
⸺ Research
Areas of study
Cell proliferation in vitro
Commonly used as a supplement in cell culture media to support growth and viability of mammalian cell lines.
Muscle and tissue models
Animal studies examine protein synthesis and hypertrophy signalling under sustained IGF-1 receptor activation.
Metabolic signalling
Preclinical work investigates glucose uptake and insulin-pathway crossover effects.
Summarised from preclinical literature for informational purposes only. Not medical or veterinary advice. Synova Research products are sold strictly for in-vitro and laboratory research.
⸺ Details
Specification
- CAS
- 946870-92-4
- Intended use
- Research use only.
- Storage
- Lyophilised: cool, dry, dark. Reconstituted: refrigerate at 2–8°C.
- Solubility
- Vial holds up to 3mL.
- Shelf life
- Lyophilised: up to 24 months. Reconstituted: 4–6 weeks refrigerated.
- Handling
- Maintain sterile technique.
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