⸺ Synova Research
Cagrilintide
Long-acting amylin analogue researched for appetite regulation and weight management, often paired with GLP-1 agonists in metabolic studies.
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Independently tested
COA on request
Next-day UK dispatch
Order before 2pm
Research use only
Not for human consumption
⸺ Important
- • Bacteriostatic water not included
- • Syringes not included
- • Peptides sold in lyophilized form
- • Strictly for laboratory research
⸺ Overview
About Cagrilintide
Cagrilintide is a synthetic long-acting analogue of amylin, a peptide hormone co-secreted with insulin from pancreatic beta cells. Researchers investigate it for satiety signalling, slowed gastric emptying and combined effects when paired with GLP-1 receptor agonists such as Semaglutide or Retatrutide.
⸺ Mechanism of Action
How it works
Cagrilintide acts on amylin and calcitonin receptors in the central nervous system, modulating satiety and gastric motility. In animal studies, this produces reduced food intake and changes in body composition, with additive effects observed alongside incretin agonists.
⸺ Research
Areas of study
Appetite signalling
Rodent studies demonstrate reduced food intake via central amylin-receptor pathways, with effects sustained over chronic dosing.
Combination with GLP-1 agonists
Preclinical work pairing Cagrilintide with GLP-1 receptor agonists reports additive effects on body weight and glycaemic markers.
Gastric emptying
Animal models show slower gastric emptying, supporting hypotheses around prolonged satiety following meals.
Summarised from preclinical literature for informational purposes only. Not medical or veterinary advice. Synova Research products are sold strictly for in-vitro and laboratory research.
⸺ Details
Specification
- CAS
- 1415456-99-3
- Intended use
- Research use only. Reconstitute with bacteriostatic water (sold separately).
- Storage
- Lyophilised: cool, dry, away from sunlight. Reconstituted: refrigerate at 2–8°C.
- Solubility
- Bacteriostatic water. Vial holds up to 3mL.
- Shelf life
- Lyophilised: up to 24 months. Reconstituted: 4–6 weeks refrigerated.
- Handling
- Sterile technique throughout.
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Semaglutide
Synthetic analogue of the GLP-1 hormone used in research to study glucose regulation, insulin secretion and the incretin response.